This is an auxiliary molecular diagnostic test that can be used when a malignant tumor is suspected in a companion dog's bladder, urethra, or prostate.

Mutation of the BRAF gene is detected in about 80% of transitional cell carcinomas in companion dogs, and as it is known as a causative gene for malignant tumors, it can be used as one of the companion cancer diagnostic tools. The presence of mutations in the BRAF gene that cancer cells can express is tested by using a companion dog’s urine and blood. The test can be performed with tissue from surgery or biopsy.